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The syndrome is characterized by jaundice and fatty and skinny hyperlipidemia and is associated fatty and skinny with striking microvesicular steatosis and abundant giant mitochondria observed on liver biopsy. TREATMENT Section 6 of 10 Author Information fatty and skinny Introduction Clinical Differentials Workup Treatment Medication Follow-up Miscellaneous Bibliography Although alcohol-induced hyperhomocysteinemia (which has been associated with endoplasmic reticulum stress leading to apoptosis and up-regulation of lipid synthesis) and its correction by betaine have been studied in animal models, no definite role of the use of betaine in alcoholic fatty liver in humans is available. Consultations: Offer alcohol rehabilitation to all patients, with an understanding of the addictive problem of alcoholism.Counsel patients on the detrimental effects of alcohol on the current liver problem and the likely progression to a more advanced form of liver disease with continued alcohol use.Diet:
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